For anyone in treatment for Lyme disease, they may find it alarming to discover that instead of getting better, all their symptoms suddenly take a turn for the worse. This worsening, called the Herxheimer reaction Lyme, is temporary but a very real part of the healing process. Knowing what it is–and how to handle it–can make a big difference.
What Causes Herxheimer Reactions?
A Herxheimer Reaction (often abbreviated to “Herx”) occurs when bacteria die off too rapidly during herbal or antibiotic treatment. As these dead bacteria release toxins into your blood, your body begins to work hard to remove them quickly in an attempt to flush them out.
The result? Symptoms suddenly flare up. It’s as if you’re becoming sicker—but really it is your body reacting to rapid die-off of Borrelia (the Lyme Disease bacteria) and co-infections.
Common Symptoms to Watch For
It feels like the usual Lyme symptoms, only turned up a notch. You may have:
- Brain fog or extreme fatigue
- Headaches or migraines
- Muscle and joint pain
- Fever, chills, or night sweats
- Nausea or stomach issues
- Mood swings or bad temper
- Dizziness or sleep problems
Symptoms usually start a few hours to two days after starting treatment and last for several days — or much longer, depending on how well your body can detoxify itself.
Why It’s (Surprisingly) a Good Sign
Even though it feels terrible, a Herxheimer reaction means your treatment is working. The body is fighting back–and winning. The increased symptoms are actually a sign that the bacteria are being killed off.
Nonetheless, you don’t want to suffer needlessly. The goal is to support your body so it can recover more smoothly.
One Can Reduce the Effects of Herxheimer Reaction in a Number of Different Ways
You may not be able to avoid a Herx reaction entirely, but you can make it easier on your body. Consider these strategies:
- Keep hydrated: Drink more water than usual to help flush out toxins.
- Support detox organs: Milk thistle or dandelion root are herbs that can help the liver and kidneys (ask for your doctor’s opinion).
- Detox baths: Epsom salt or bicarbonate of soda baths will help relax muscles and encourage sweating.
- Use binding agents: Activated charcoal or bentonite clay can bind toxins in the gut.
- Rest, don’t push: Give your body the room it needs to recover by resting rather than pushing it; sleep is the best medicine.
- Talk to your doctor: If your symptoms are severe, your practitioner might lower your treatment dose for a while.
When to Call Your Doctor
Most Herx reactions are uncomfortable but manageable. However, seek medical attention immediately if you have:
- High fever
- Chest pains or shortness of breath
- Confusion or seizures
- Numbness or loss of function
Never assume it’s just a “Herx reaction” When something doesn’t feel right, seek help.
Conclusion
Experiencing a Herx reaction during Lyme treatment is tough to bear–but often times it is indicative of the road to healing. Be patient, listen to your body and follow strategies supporting detox and reducing stress.
So, with time, persistence and the right kind of care, you’ll begin to feel better–and much more on the mend towards recovery.










