Cholera: Symptoms, Treatment & Vaccine Guide

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Cholera

An intestinal infection usually acquired from food or water contaminated with Vibrio cholerae.

SymptomsMany infections are mild; severe cases cause profuse watery diarrhea, vomiting, leg cramps, and rapid dehydration.
Typical durationSymptoms commonly begin within hours to five days of exposure.
Vaccine statusTravel vaccine

Symptoms and what to notice

Many infections are mild; severe cases cause profuse watery diarrhea, vomiting, leg cramps, and rapid dehydration.

How long can it last?

Symptoms commonly begin within hours to five days of exposure.

How serious is Cholera?

Severe dehydration can become fatal within hours without treatment.

Treatment and management

Immediate oral rehydration is central; severe cases need intravenous fluids and sometimes antibiotics.

Is there a vaccine—and who should receive it?

Oral cholera vaccine may be recommended for eligible U.S. travelers to areas with active transmission. Timing and age eligibility should be checked on the current CDC page.

Official U.S. guidance

Read the current CDC guidance for Cholera →

Cost: Patient cost varies by insurance, provider, location, and eligibility. Many recommended vaccines are covered with no out-of-pocket cost under qualifying plans, and eligible children may receive vaccines through the Vaccines for Children program. CDC price lists are purchasing benchmarks—not guaranteed patient prices. CDC price context.

Health note: This page gives general U.S. educational information. Vaccine choice and timing depend on age, medical history, previous doses, pregnancy, travel, exposure, and current public-health guidance. Seek urgent care for severe or rapidly worsening symptoms.