Mpox: Symptoms, Treatment & Vaccine Guide

← Diseases beginning with M
Risk-based vaccine

Mpox

A viral disease spread mainly through close personal contact with an infected person or contaminated materials.

SymptomsA painful or itchy rash, fever, chills, swollen lymph nodes, fatigue, muscle aches, headache, or respiratory symptoms.
Typical durationIllness commonly lasts two to four weeks.
Vaccine statusRisk-based vaccine

Symptoms and what to notice

A painful or itchy rash, fever, chills, swollen lymph nodes, fatigue, muscle aches, headache, or respiratory symptoms.

How long can it last?

Illness commonly lasts two to four weeks.

How serious is Mpox?

Most recover, but severe disease can occur, particularly with substantial immune suppression, pregnancy, or certain skin conditions.

Treatment and management

Supportive care and pain control are common; public-health or specialist teams may use investigational or special-access antivirals for severe/high-risk illness.

Is there a vaccine—and who should receive it?

JYNNEOS is generally given as two doses 28 days apart to people with specified exposure risk or after certain exposures. Routine vaccination is not recommended for everyone.

Official U.S. guidance

Read the current CDC guidance for Mpox →

Cost: Patient cost varies by insurance, provider, location, and eligibility. Many recommended vaccines are covered with no out-of-pocket cost under qualifying plans, and eligible children may receive vaccines through the Vaccines for Children program. CDC price lists are purchasing benchmarks—not guaranteed patient prices. CDC price context.

Health note: This page gives general U.S. educational information. Vaccine choice and timing depend on age, medical history, previous doses, pregnancy, travel, exposure, and current public-health guidance. Seek urgent care for severe or rapidly worsening symptoms.